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Spicy Watermelon Margaritas

  • Author: Molly
  • Total Time: 20 minutes
  • Yield: 2 cocktails (easily multiplied) 1x


These Spicy Watermelon Margaritas are the perfect summer cocktail! They feature a spicy serrano syrup, fresh watermelon juice, and a salty Tajin rim! Spicy, smoky, sweet, and tangy all at once. I could sip on these all summer long…all that’s missing is some chips and salsa!



For the Simple Syrup:

For the Watermelon Juice:

  • 5 cups fresh watermelon, cubed (see NOTE)

For 2 Margaritas:

  • 4 oz watermelon juice
  • 4 oz silver tequila
  • 4 oz freshly squeezed lime juice
  • 2 oz orange liqueur (Cointreau is my fave, but triple sec works too!)
  • 2 oz spicy simple syrup (or to taste)

For Rimming the Glasses:

  • 1 lime wedge
  • 1 tablespoon coarse salt
  • 1 tablespoon sugar
  • 2 teaspoon Tajin seasoning

For Serving:

  • Ice
  • Watermelon wedges
  • Sliced serrano peppers
  • Lime wedges


For the Simple Syrup:

Make the simple syrup first and allow to cool while you prep the other ingredients.


Make the Watermelon Juice:

Add watermelon to a blender and blend on high for 30 seconds or until the watermelon is completely blended and liquified.


For 2 Cocktails:

  1. To a large shaker filled with ice, add the watermelon juice, tequila, lime juice, orange liqueur, and cooled simple syrup.
  2. Shake vigorously for a few seconds to thoroughly mix and chill the ingredients.

To Serve:

  1. In a shallow bowl, mix together the salt, sugar, and Tajin.
  2. Run a lime slice around the edges of your serving glasses and then dip the rims in salt mixture.
  3. Fill the glasses with ice.
  4. Pour the margarita mixture into the glasses, garnish with watermelon wedges, limes, or serrano pepper slices, and serve immediately.



  • You can use any hot pepper here. Serranos add a good amount of heat and add a great flavor to the syrup. Jalapeños would also work great!
  • If you want to make this even easier, you can use store-bought watermelon juice. It doesn’t need to be freshly blended juice. This brand is my favorite. I have made this both ways and both are fabulous.
  • This recipe will make extra simple syrup and watermelon juice. Perfect for making a larger batch of margaritas!
  • Prep Time: 10 minutes
  • Cook Time: 10 minutes
  • Category: cocktails

Keywords: spicy watermelon margarita, spicy watermelon margarita with tajin, margarita with tajin rim, homemade watermelon juice, serrano syrup, serrano watermelon margaritas